Carbamic acid, [1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methyl-, phenylmethyl ester (9CI)
benzyl [1-(1H-indol-3-yl)-2-pyrrolidin-1-ylethyl]methylcarbamate
CAS: 886363-10-6
Molecular Formula: C23H27N3O2
Carbamic acid, [1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methyl-, phenylmethyl ester (9CI) - Names and Identifiers
| Name | benzyl [1-(1H-indol-3-yl)-2-pyrrolidin-1-ylethyl]methylcarbamate |
| Synonyms | 1-Pyrrolidin-2-(N-Cbz-N-methyl)amino-2-(3'-indole)ethane benzyl [1-(1H-indol-3-yl)-2-pyrrolidin-1-ylethyl]methylcarbamate benzyl 1-(1H-indol-3-yl)-2-(pyrrolidin-1-yl)ethyl(methyl)carbamate Benzyl [1-(1H-indol-3-yl)-2-(pyrrolidin-1-yl)ethyl]methylcarbamate [1-(1H-Indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methylcarbamic acid phenylmethyl ester Carbamic acid, N-[1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]-N-methyl-, phenylmethyl ester Carbamic acid, [1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methyl-, phenylmethyl ester (9CI) |
| CAS | 886363-10-6 |
| InChI | InChI=1/C23H27N3O2/c1-25(23(27)28-17-18-9-3-2-4-10-18)22(16-26-13-7-8-14-26)20-15-24-21-12-6-5-11-19(20)21/h2-6,9-12,15,22,24H,7-8,13-14,16-17H2,1H3 |
Carbamic acid, [1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methyl-, phenylmethyl ester (9CI) - Physico-chemical Properties
| Molecular Formula | C23H27N3O2 |
| Molar Mass | 377.485 |
| Density | 1.209g/cm3 |
| Boling Point | 566.9°C at 760 mmHg |
| Flash Point | 296.6°C |
| Vapor Presure | 7.21E-13mmHg at 25°C |
| Refractive Index | 1.636 |
Carbamic acid, [1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methyl-, phenylmethyl ester (9CI) - Introduction
benzyl [1-(1H-indol-3-yl)-methylcarbamate] is an organic compound with the chemical formula C24H25N3O2.
Properties of the compound:
-Appearance: Colorless solid
-melting point: about 80-85 ℃
-Boiling point: about 495-498 ℃
-Solubility: Soluble in organic solvents such as chloroform, ethanol and dichloromethane
Use of the compound:
-Pharmaceutical intermediates: can be used to synthesize biologically active compounds, such as drugs and pesticides.
-Chemical research: can be used as a reagent, catalyst or ligand in organic synthesis.
Preparation of the compound:
The compound is generally synthesized by chemical synthesis, the specific steps are as follows:
1. A pyrrolidine group is reacted with a N-Cbz-N-methylamino compound to obtain a 1-pyrrolidinyl-2-(N-Cbz-N-methyl) amino compound.
2. The 1-pyrrolidinyl -2-(N-Cbz-N-methyl) amino compound is reacted with 3 '-indoleacetic acid chloride, and the target product is obtained under alkali or alkali-free conditions.
Safety information for this compound:
Because the compound is involved in organic synthesis and pharmaceutical research, it is necessary to pay attention to safety during operation and comply with relevant laboratory operating specifications. This compound is irritating and toxic, and direct contact with skin, eyes and respiratory tract should be avoided, and inhalation of its dust should be avoided. Operations should be carried out in a well-ventilated area and equipped with appropriate personal protective equipment, such as protective glasses and gloves. The compound should be stored in a dry, cool, well-ventilated place. If accidental exposure occurs, rinse immediately with plenty of water and seek medical help.
Properties of the compound:
-Appearance: Colorless solid
-melting point: about 80-85 ℃
-Boiling point: about 495-498 ℃
-Solubility: Soluble in organic solvents such as chloroform, ethanol and dichloromethane
Use of the compound:
-Pharmaceutical intermediates: can be used to synthesize biologically active compounds, such as drugs and pesticides.
-Chemical research: can be used as a reagent, catalyst or ligand in organic synthesis.
Preparation of the compound:
The compound is generally synthesized by chemical synthesis, the specific steps are as follows:
1. A pyrrolidine group is reacted with a N-Cbz-N-methylamino compound to obtain a 1-pyrrolidinyl-2-(N-Cbz-N-methyl) amino compound.
2. The 1-pyrrolidinyl -2-(N-Cbz-N-methyl) amino compound is reacted with 3 '-indoleacetic acid chloride, and the target product is obtained under alkali or alkali-free conditions.
Safety information for this compound:
Because the compound is involved in organic synthesis and pharmaceutical research, it is necessary to pay attention to safety during operation and comply with relevant laboratory operating specifications. This compound is irritating and toxic, and direct contact with skin, eyes and respiratory tract should be avoided, and inhalation of its dust should be avoided. Operations should be carried out in a well-ventilated area and equipped with appropriate personal protective equipment, such as protective glasses and gloves. The compound should be stored in a dry, cool, well-ventilated place. If accidental exposure occurs, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:18:00
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Carbamic acid, [1-(1H-indol-3-yl)-2-(1-pyrrolidinyl)ethyl]methyl-, phenylmethyl ester (9CI)
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